WHY YOUR SKIN NEEDS VITAMIN C (THD), NOT ORAL SUPPLEMENTS

Vitamin C is required for collagen synthesis

You literally cannot make collagen without vitamin C. It is a cofactor for proline and lysine hydroxylase, enzymes that form stable collagen fibers.

Low vitamin C = weak collagen = wrinkles, sagging, thin skin.

Topical vitamin C restores:

  • Firmness
  • Elasticity
  • Smoothness
  • Structural strength

THD ascorbate is excellent for this because it penetrates into the dermis, where collagen is made.

THD Ascorbate penetrates far better than regular vitamin C

Even if you take high-dose oral vitamin C, almost none reaches the skin.

Your skin has:

  • Poor blood flow compared to internal organs
  • Low priority for nutrient delivery
  • A barrier (stratum corneum) that blocks hydrophilic molecules like L-ascorbic acid

So skin levels remain suboptimal, especially with aging.

Topical application is the only way to saturate skin vitamin C to levels needed for anti-aging and repair.

Vitamin C protects skin from UV, pollution, and oxidative stress

Skin is constantly exposed to:

  • UV radiation
  • Pollution
  • Free radical damage
  • Blue light
  • Inflammation

Vitamin C neutralizes this oxidative stress and prevents:

  • Dark spots
  • Fine lines
  • Collagen breakdown
  • DNA damage

But you only get this effect when the vitamin C is inside the skin, which topical THD delivers exceptionally well.

THD Ascorbate penetrates far better than regular vitamin C

Traditional vitamin C (L-ascorbic acid):

  • Is water-soluble
  • Unstable
  • Oxidizes quickly
  • Struggles to penetrate the skin barrier

THD ascorbate:

  • Is fat-soluble → penetrates more deeply
  • Is extremely stable (doesn't oxidize easily)
  • Converts to active vitamin C inside the skin
  • Has higher bioavailability
  • Produces stronger collagen and brightening results at lower concentrations.

This is why THD is used in higher-end medical-grade products.

Topical vitamin C targets melanocytes (pigment cells)

Skin lightening and dark spot correction require direct action inside pigment cells.

Oral vitamin C does almost nothing for hyperpigmentation.

Topical THD:

  • Reduces melanin production
  • Brightens uneven tone
  • Fades dark spots
  • Helps reverse sun damage

Again, this can only happen with topical-skin level saturation.

WHY YOUR SKIN NEEDS VITAMIN E MIXED TOCOPHEROLS (NOT JUST ALPHA)

Your skin is exposed to oxidative damage that only mixed tocopherols can neutralize

Each tocopherol type neutralizes different kinds of free radicals.

  • Alpha tocopherol handles a narrow range of lipid peroxides.
  • Gamma-tocopherol neutralizes reactive nitrogen species (RNS) from pollution and inflammation.
  • Delta and beta target deeper-layer lipid radicals.

If you only apply alpha-tocopherol, you're missing the antioxidants needed to handle up to 60% of the oxidative stress coming from pollution, UV, and inflammation.

The skin's lipid barrier naturally contains mixed tocopherols, not just alpha.

Gamma-tocopherol is the dominant form in the skin (not alpha!)

Research shows the skin relies heavily on gamma-tocopherol because it:

  • Neutralizes peroxynitrite (a highly damaging radical)
  • Reduces inflammation in the epidermis
  • Protects ceramides and skin lipids
  • Stabilizes cell membranes

Topical alpha-tocopherol alone cannot do this.

That's why mixed tocopherols restore the antioxidant profile your skin naturally uses.

Mixed tocopherols prevent alpha-tocopherol from oxidizing

Pure alpha-tocopherol oxidizes quickly on the skin.

But when you include gamma and delta, they:

  • Regenerate alpha-tocopherol
  • Slow its oxidation
  • Prevent it from becoming pro-oxidant
  • Improve its stability inside the formula and inside your skin

Without gamma and delta, alpha can actually break down faster under UV exposure.

They work together to protect the skin barrier

Your skin barrier is made of lipids:

  • Ceramides
  • Cholesterol
  • Fatty acids

Mixed tocopherols protect all these lipids from oxidation and help recovery.

Benefits include:

  • Smoother skin
  • Less dryness
  • Less transepidermal water loss
  • Stronger resilience

Alpha alone doesn't give full lipid protection.

Mixed tocopherols help stabilize other skincare actives

They synergize with:

  • Vitamin C (THD or LAA)
  • CoQ10
  • Astaxanthin
  • Retinoids
  • Peptides

Gamma- and delta-tocopherol increase the antioxidant network of the skin, helping these actives perform better and last longer in the skin.

WHY YOUR SKIN NEEDS TOPICAL ASTAXANTHIN (NOT ORAL)

The skin receives very little astaxanthin from the bloodstream

When you take astaxanthin orally, your body sends it to:

  • The eyes
  • The brain
  • The heart
  • The nervous system

The skin gets leftovers, and the concentration is too low to trigger the anti-aging effects astaxanthin is known for.

Topical application bypasses the bloodstream and delivers it straight into:

  • The epidermis
  • Skin lipids
  • Mitochondrial membranes in skin cells
  • This is where most UV/oxidative damage occurs.

Astaxanthin is fat-soluble - perfect for penetrating skin membranes

Because astaxanthin is lipophilic (fat-loving), it easily absorbs into:

  • Cell membranes
  • Mitochondrial membranes
  • The lipid barrier

This placement is exactly where UV damage destroys collagen.

Topical delivery ensures it's highly concentrated in the skin's lipid layers, where it can act as a "shield".

Oral astaxanthin can't provide enough UV/oxidation protection to skin

Typically, astaxanthin reduces:

  • UV-induced collagen breakdown
  • Inflammation
  • Mitochondrial oxidative damage
  • Sun-induced aging signs

It's actually more effective than vitamin C at preventing oxidative damage inside the membrane.

You cannot get this level of membrane saturation via oral supplements.

Astaxanthin protects fibroblasts - the cells that create collagen

Fibroblasts sit in the dermis, generating collagen.

Topically applied astaxanthin:

  • Reduces oxidative stress
  • Keeps fibroblasts functioning longer
  • Helps maintain firmness and elasticity
  • Slows the collapse and thinning of the dermal layer

This is a major reason skin starts to sag with age - fibroblasts burn out.

Astaxanthin protects them where they live.

Oral astaxanthin takes weeks to show minimal skin-level effects

Even at high doses (12-24 mg/day), blood-delivered astaxanthin:

  • Reaches skin slowly
  • In small amounts
  • Over many weeks
  • And peaks low

Topical application produces meaningful antioxidant concentration within hours, not weeks.

WHY YOUR SKIN NEEDS TOPICAL CoQ10 (AND NOT ORAL)

Skin cells burn huge amounts of energy (ATP) to repair damage

Skin is constantly:

  • Fighting UV radiation
  • Rebuilding collagen
  • Replacing cells
  • Repairing oxidative damage

All of this requires mitochondrial ATP, and CoQ10 is literally part of the machinery that produces it.

Lower CoQ10 = slower repair = aging signs.

By age 40, natural CoQ10 in the skin drops 25-30%.

By age 60, it drops over 50%.

CoQ10 is one of the few oxidants that protects inside the cell membrane

UV light creates oxidative stress that destroys:

  • Collagen
  • Elastin
  • Lipids in the skin barrier

CoQ10 sits in the lipid membrane, neutralizing free radicals where vitamin C and many other antioxidants cannot reach.

This reduces:

  • Wrinkles
  • Sagging
  • Hyperpigmentation
  • Inflammation

CoQ10 supports collagen-producing fibroblasts

Fibroblasts (the cells that generate collagen) lose efficiency with age as their mitochondria weaken.

Topical CoQ10 has been shown to:

  • Increase collagen synthesis
  • Improve firmness and elasticity
  • Reduce wrinkle depth

It's one of the few ingredients proven to help at a mitochondria level.

CoQ10 needs to be applied topically (oral supplements don't reach the skin well)

Oral CoQ10 goes to organs first:

1. Heart

2. Liver

3. Brain

4. Muscles

The skin is treated by the body as "cosmetic," so it gets almost no supplemental CoQ10, even at high doses.

On top of that:

  • CoQ10 is large and lipophilic, slow to travel through the bloodstream
  • The skin's outer layer (stratum corneum) is a barrier
  • Blood flow to the skin is lower than internal organs

Oral COQ10 barely increases skin CoQ10 levels.

What topical COQ10 typically does

Studies show topical CoQ10:

  • Reduces wrinkle depth
  • Improves skin smoothness
  • Lowers oxidative stress from UV exposure
  • Stabilizes skin lipids
  • Supports collagen
  • Helps protect mitochondrial function

It's not hype - it's one of the few actives with mitochondrial-level impact.

WHY YOUR SKIN NEEDS VITAMIN C (THD), NOT ORAL SUPPLEMENTS
Vitamin C is required for collagen synthesis

You literally cannot make collagen without vitamin C. It is a cofactor for proline and lysine hydroxylase, enzymes that form stable collagen fibers.

Low vitamin C = weak collagen = wrinkles, sagging, thin skin.

Topical vitamin C restores:

  • Firmness
  • Elasticity
  • Smoothness
  • Structural strength

THD ascorbate is excellent for this because it penetrates into the dermis, where collagen is made.
THD Ascorbate penetrates far better than regular vitamin C

Even if you take high-dose oral vitamin C, almost none reaches the skin.

Your skin has:

  • Poor blood flow compared to internal organs
  • Low priority for nutrient delivery
  • A barrier (stratum corneum) that blocks hydrophilic molecules like L-ascorbic acid

So skin levels remain suboptimal, especially with aging.

Topical application is the only way to saturate skin vitamin C to levels needed for anti-aging and repair.
Vitamin C protects skin from UV, pollution, and oxidative stress

Skin is constantly exposed to:

  • UV radiation
  • Pollution
  • Free radical damage
  • Blue light
  • Inflammation

Vitamin C neutralizes this oxidative stress and prevents:

  • Dark spots
  • Fine lines
  • Collagen breakdown
  • DNA damage

But you only get this effect when the vitamin C is inside the skin, which topical THD delivers exceptionally well.
THD Ascorbate penetrates far better than regular vitamin C

Traditional vitamin C (L-ascorbic acid):

  • Is water-soluble
  • Unstable
  • Oxidizes quickly
  • Struggles to penetrate the skin barrier

THD ascorbate:

  • Is fat-soluble → penetrates more deeply
  • Is extremely stable (doesn't oxidize easily)
  • Converts to active vitamin C inside the skin
  • Has higher bioavailability
  • Produces stronger collagen and brightening results at lower concentrations.

This is why THD is used in higher-end medical-grade products.
Topical vitamin C targets melanocytes (pigment cells)

Skin lightening and dark spot correction require direct action inside pigment cells.

Oral vitamin C does almost nothing for hyperpigmentation.

Topical THD:

  • Reduces melanin production
  • Brightens uneven tone
  • Fades dark spots
  • Helps reverse sun damage

Again, this can only happen with topical-skin level saturation.

WHY YOUR SKIN NEEDS VITAMIN E MIXED TOCOPHEROLS (NOT JUST ALPHA)
Your skin is exposed to oxidative damage that only mixed tocopherols can neutralize

Each tocopherol type neutralizes different kinds of free radicals.

  • Alpha tocopherol handles a narrow range of lipid peroxides.
  • Gamma-tocopherol neutralizes reactive nitrogen species (RNS) from pollution and inflammation.
  • Delta and beta target deeper-layer lipid radicals.

If you only apply alpha-tocopherol, you're missing the antioxidants needed to handle up to 60% of the oxidative stress coming from pollution, UV, and inflammation.

The skin's lipid barrier naturally contains mixed tocopherols, not just alpha.
Gamma-tocopherol is the dominant form in the skin (not alpha!)

Research shows the skin relies heavily on gamma-tocopherol because it:

  • Neutralizes peroxynitrite (a highly damaging radical)
  • Reduces inflammation in the epidermis
  • Protects ceramides and skin lipids
  • Stabilizes cell membranes

Topical alpha-tocopherol alone cannot do this.

That's why mixed tocopherols restore the antioxidant profile your skin naturally uses.
Mixed tocopherols prevent alpha-tocopherol from oxidizing

Pure alpha-tocopherol oxidizes quickly on the skin.

But when you include gamma and delta, they:

  • Regenerate alpha-tocopherol
  • Slow its oxidation
  • Prevent it from becoming pro-oxidant
  • Improve its stability inside the formula and inside your skin

Without gamma and delta, alpha can actually break down faster under UV exposure.
They work together to protect the skin barrier

Your skin barrier is made of lipids:

  • Ceramides
  • Cholesterol
  • Fatty acids

Mixed tocopherols protect all these lipids from oxidation and help recovery.

Benefits include:

  • Smoother skin
  • Less dryness
  • Less transepidermal water loss
  • Stronger resilience

Alpha alone doesn't give full lipid protection.
Mixed tocopherols help stabilize other skincare actives

They synergize with:

  • Vitamin C (THD or LAA)
  • CoQ10
  • Astaxanthin
  • Retinoids
  • Peptides

Gamma- and delta-tocopherol increase the antioxidant network of the skin, helping these actives perform better and last longer in the skin.

WHY YOUR SKIN NEEDS TOPICAL ASTAXANTHIN (NOT ORAL)
The skin receives very little astaxanthin from the bloodstream

When you take astaxanthin orally, your body sends it to:

  • The eyes
  • The brain
  • The heart
  • The nervous system

The skin gets leftovers, and the concentration is too low to trigger the anti-aging effects astaxanthin is known for.

Topical application bypasses the bloodstream and delivers it straight into:

  • The epidermis
  • Skin lipids
  • Mitochondrial membranes in skin cells
  • This is where most UV/oxidative damage occurs.
Astaxanthin is fat-soluble - perfect for penetrating skin membranes

Because astaxanthin is lipophilic (fat-loving), it easily absorbs into:

  • Cell membranes
  • Mitochondrial membranes
  • The lipid barrier

This placement is exactly where UV damage destroys collagen.

Topical delivery ensures it's highly concentrated in the skin's lipid layers, where it can act as a "shield".
Oral astaxanthin can't provide enough UV/oxidation protection to skin

Typically, astaxanthin reduces:

  • UV-induced collagen breakdown
  • Inflammation
  • Mitochondrial oxidative damage
  • Sun-induced aging signs

It's actually more effective than vitamin C at preventing oxidative damage inside the membrane.

You cannot get this level of membrane saturation via oral supplements.
Astaxanthin protects fibroblasts - the cells that create collagen

Fibroblasts sit in the dermis, generating collagen.

Topically applied astaxanthin:

  • Reduces oxidative stress
  • Keeps fibroblasts functioning longer
  • Helps maintain firmness and elasticity
  • Slows the collapse and thinning of the dermal layer

This is a major reason skin starts to sag with age - fibroblasts burn out.

Astaxanthin protects them where they live.
Oral astaxanthin takes weeks to show minimal skin-level effects

Even at high doses (12-24 mg/day), blood-delivered astaxanthin:

  • Reaches skin slowly
  • In small amounts
  • Over many weeks
  • And peaks low

Topical application produces meaningful antioxidant concentration within hours, not weeks.

WHY YOUR SKIN NEEDS TOPICAL CoQ10 (AND NOT ORAL)
Skin cells burn huge amounts of energy (ATP) to repair damage

Skin is constantly:

  • Fighting UV radiation
  • Rebuilding collagen
  • Replacing cells
  • Repairing oxidative damage

All of this requires mitochondrial ATP, and CoQ10 is literally part of the machinery that produces it.

Lower CoQ10 = slower repair = aging signs.

By age 40, natural CoQ10 in the skin drops 25-30%.

By age 60, it drops over 50%.
CoQ10 is one of the few oxidants that protects inside the cell membrane

UV light creates oxidative stress that destroys:

  • Collagen
  • Elastin
  • Lipids in the skin barrier

CoQ10 sits in the lipid membrane, neutralizing free radicals where vitamin C and many other antioxidants cannot reach.

This reduces:

  • Wrinkles
  • Sagging
  • Hyperpigmentation
  • Inflammation
CoQ10 supports collagen-producing fibroblasts

Fibroblasts (the cells that generate collagen) lose efficiency with age as their mitochondria weaken.

Topical CoQ10 has been shown to:

  • Increase collagen synthesis
  • Improve firmness and elasticity
  • Reduce wrinkle depth

It's one of the few ingredients proven to help at a mitochondria level.
CoQ10 needs to be applied topically (oral supplements don't reach the skin well)

Oral CoQ10 goes to organs first:

1. Heart

2. Liver

3. Brain

4. Muscles

The skin is treated by the body as "cosmetic," so it gets almost no supplemental CoQ10, even at high doses.

On top of that:

  • CoQ10 is large and lipophilic, slow to travel through the bloodstream
  • The skin's outer layer (stratum corneum) is a barrier
  • Blood flow to the skin is lower than internal organs

Oral COQ10 barely increases skin CoQ10 levels.
What topical COQ10 typically does

Studies show topical CoQ10:

  • Reduces wrinkle depth
  • Improves skin smoothness
  • Lowers oxidative stress from UV exposure
  • Stabilizes skin lipids
  • Supports collagen
  • Helps protect mitochondrial function

It's not hype - it's one of the few actives with mitochondrial-level impact.